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sequencing, flow cytometry, multiplex immunofluorescence, spatial transcriptomics, and standard molecular biology approaches. A computational component may also be available, depending on the skills and
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transcriptomics) in conjuction with intravital imaging and proximity labelling tools to define the dynamic interaction of immune cells in cancer. The candidate will need to master both complex 'wet lab' techniques
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of breast cancer patients (the largest of their kind; making extensive use of imaging mass cytometry and spatial transcriptomics) that span observational studies and clinical trials. We must precisely define
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NE*, Wang G* et al. Enhancing transcription replication conflict targets ecDNA-positive cancers. Nature 635, 210-218 (2024). PMID: 39506153 Wang G, et al. Spatial organization of the transcriptome in
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on developing probabilistic latent-variable methods for large and structured biological data, with applications in genomics, spatial transcriptomics, and fluorescence imaging. High-dimensional and structured
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the 36 months immediately before the March 1st, 2027. Experience and knowledge: Required: Experience with next-generation sequencing, molecular diagnostics and/or transcriptomic, proteomic or metabolomic
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this project is to exploit transcriptomic data sets for the discovery of new therapeutic antibodies. The lab has a very translational focus, running a tech development lab on the EPFL campus and a translational
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well as the analysis of diverse multiomic data types (genomics, epigenomics, transcriptomics) towards identification of biomarkers of neurogenetic disease. The appointee will also be involved in teaching and training
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, reducing agricultural productivity, grain quality, and food and feed safety. The research will integrate genome sequences, genetic variation, transcriptomic profiles, functional annotations, protein
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responses to cancer immunotherapy. By integrating human clinical studies with mechanistic mouse models, the lab uses high-dimensional flow cytometry, single-cell transcriptomics, multiplex proteomics, and in