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to modulate plasma vWF. 2. Translational hematology, using patient-derived samples (blood and others) together with genomic, transcriptomic, and proteomic approaches to investigate mechanisms of thrombosis
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arteriovenous malformations, using patient cohorts and surgical specimens together with whole exome sequencing and a range of transcriptomic, epigenomic, and spatial methods. The successful candidate will analyze
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-based perturbations, base/prime editing, and targeted epigenetic modulation). Functional genomics in neuronal systems, including transcriptomic and epigenomic profiling. Model systems such as human iPSC
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evolutionarily conserved structured RNAs and candidate mammalian riboswitches from large genomics and transcriptomics datasets. The position will involve close collaboration with experimental scientists who will
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. Preferred: Integration of wet lab findings with computational analysis of multi-omic data (e.g., structural variants, transcriptomics) using R or Python pipelines. Mentoring and Professional Development
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) - Perform single-cell and spatial multi-omics analyses at scale - Integrate genetics with longitudinal transcriptome, clinical, biosensor, trajectories - Contribute to discovery of disease mechanisms and
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allograft rejection/failure is highly desirable. The approaches are founded on interpretation of large data sets from human genome level sequence data and/or mouse cell type specific transcriptome sequence
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spatial transcriptomic platforms. With the breadth of ongoing research projects, there are ample opportunities to tailor the needs of the lab to the skillset and interests of the individual. Candidates with
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these questions and advance novel therapeutics for infertility. The candidate will use bioinformatic and computational tools to analyze single-cell and spatial transcriptomic data. Your work will be central to
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, single-cell mRNA transcriptomics, and quantitative/functional antibody assays in human and animal models. Responsibilities The postdoctoral associate will – based on their research interest: Design and