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Field
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applications for a Postdoctoral Researcher to join a dynamic, interdisciplinary research team investigating the molecular mechanisms of subcellular RNA transport and post transcriptional regulation mediated by
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of RNA-binding proteins involved in melanoma progression. Appropriate candidates should have expertise on 2D-PAGE and analysis of protein phosphorylation. Candidates must hold a PhD degree and be fairly
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that variants have on PR-DUB and PRC1 function - using methods such as CUT&Tag, Captify, RNA-seq, immunoprecipitation followed by mass spectrometry and high throughput pooled CRISPR screens. The role
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projects in the laboratory integrate whole-genome sequencing (WGS), transcriptomics, single-cell RNA sequencing, antibody and systems-serology measurements, PhIP-Seq/epitope profiling, immunophenotyping, and
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progression in vivo. • Apply molecular and genomic approaches, immunofluorescence/immunohistochemistry, gene-expression analysis, RNA sequencing, and pathway analysis. Responsibilities The successful candidate
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SPECIFICS A postdoctoral position is available in Dr. Paul Babitzke’s research lab within the Center for RNA Molecular Biology and the Department of Biochemistry and Molecular Biology at Penn State
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and manipulation of RNA including RNA extraction, RT-PCR, and quantitative real-time PCR as well as functional assays (cellular and subcellular functions) and biochemical assays (protein-based work
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the experimental and bioinformatics analysis components—is essential. Proficiency in classical genomics techniques (RNA-seq, ChIP-seq, etc.) Proficiency in mouse ES cell culture and in vitro differentiation
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research group. Our research focuses on understanding how RNA regulatory mechanisms contribute to cancer progression and therapeutic responses, and on developing innovative RNA-based therapeutic strategies
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will participate in grant-funded research aimed at: · Characterizing collateral RNA cleavage by diverse Cas13 homologs and determining their RNA substrate preferences and mechanisms of activation