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Position Overview The Arbibe Laboratory at Institut Necker Enfants Malades is seeking a motivated Postdoctoral Research Fellow with strong hands-on expertise in circular RNA (circRNA) biology, to
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investigate the impact of post-transcriptional modifications of transfer RNAs (tRNAs) on stress tolerance and adaptation in clinical strains of *Escherichia coli*. The project will combine experimental
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the experimental and bioinformatics analysis components—is essential. Proficiency in classical genomics techniques (RNA-seq, ChIP-seq, etc.) Proficiency in mouse ES cell culture and in vitro differentiation
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human pathophysiology and therapy. Cell culture, protein purification, Western blotting, enzymology, proteomics, RNA-seq, immunohistochemistry and immunofluorescence, mass spectrometry, etc. Preparation
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bioinformatics, particularly single‑cell RNA‑seq, multi‑omics, and spatial transcriptomics analysis. Specific Requirements Proficiency in Python and R; familiarity with common bioinformatics tools and pipelines
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by RT-qPCR and RNA-seq); determine how GATA6 modifies the response to immunotherapy by injecting animals bearing xenografts with anti-PD1 (measurement of tumor growth, analyses of the immune
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sorting and injection of RNA and/or proteins, is also required. The agent should be able to read, understand and apply data from the scientific literature. Website for additional job details https
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on Leptospirosis. How to Apply: Send your CV and a motivation letter with at least two references to: [email protected] References: In vivo dual RNA-Seq uncovers key effectors of epithelial barrier
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and biochemical characterization of bromodomain-histone interactions, analysis of Bdf1-chromatin interactions in cells by fluorescence microscopy, and transcriptomic profiling by RNA sequencing