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Field
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position The Laboratory of Causal Systems Immunology is looking for a PhD student or postdoctoral researcher to advance in vivo perturbational screening. We have developed single-cell CRISPR technologies
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associate with specialization in immunology, cancer biology and/or radiation biology. The Postdoctoral Associate will work alongside a multidisciplinary team leveraging CRISPR screening, antibody discovery
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the team more than it benefits you. Experience in cellular genetic engineering using viral vectors, CRISPR/Cas9 systems etc. would be highly desirable, and at least a sound understanding of the principles
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. Previous experience with molecular biology techniques (Western blots, qPCR/RNAseq), experience with gene editing(CRISPR), and DNA manipulation, are all preferred. The candidate should have hands
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– signaling – proteasome – ubiquitination – multiple myeloma – mantle cell lymphoma – cancer – immunology – inflammation – infection – streptococcus – CRISPR/Cas9 – proteomics – targeted therapy Website
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therapeutic editing strategies. Research Focus Areas Neurodevelopmental disorders and the genetic and epigenetic mechanisms underlying altered neural development. Genome and epigenome editing (e.g., CRISPR
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cytometry and cell sorting is also required together with experience of advanced genome editing including cloning of CRISPR gRNAs for custom screens, base editing (including alternative specificity Cas
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-domain proteins. Research program The project will establish a targeted CRISPR-based functional screening strategy for LCCL-domain proteins in Cryptosporidium. The postdoctoral researcher will
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with experience of advanced genome editing including cloning of CRISPR gRNAs for custom screens, base editing (including alternative specificity Cas enzymes) and prime editing. Experience of off-target assays
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in knockout generation using CRISPR Experience in cellular and molecular immunology techniques, including flow cytometry, ex vivo Treg expansion, intracellular cytokine assays, and functional immune