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differentiation (ideally mouse ESCs), single cell sequencing, method development, flow cytometry/FACS, and/or CRISPR-based perturbations, data analysis. Theoretical background in epigenetics and embryonic
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-resolution microscopy Genome editing (e.g., CRISPR-based approaches) Quantitative and live-cell imaging Functional genomics The project is embedded in an interdisciplinary research environment combining
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the other postdoc included in the project. Main tasks of the postdoc Culture M. leidyi and use CRISPR-cas9 to obtain knockout strains Perform common garden experiments testing wildtype vs knockout strains
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samples obtained from in vivo cancer models (in conjunction with the Thomsen group and Histocore) and establishing explant/tissue slice cultures. Engineering cell lines and in vivo models using CRISPR and