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Field
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to study protein-protein interactions, such as co-immunoprecipitation. Experience with genetic manipulation, including CRISPR-based approaches or related techniques, is highly desirable. Expertise in
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Functions The Postdoctoral Associate will conduct research on Alzheimer Disease. -Molecular biology techniques to include, but are not limited to PCR, cloning, CRISPR and tissue culture. In addition isolation
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. Building on this platform, we combine cell biology, biochemistry, CRISPR-based approaches, organelle isolation, metabolomics and proteomics, mouse genetics, and disease models to discover principles of ER
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mechanistic interrogations using models, such as conditional knock-out or CRISPR-mediated targeted insertion. The goal is to understand T cell homeostasis in the context of viral infection, chronic infection
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Massachusetts Institute of Technology | Cambridge, Massachusetts | United States | about 1 month ago
(e.g., CRISPR screens), and/or single cell transcriptomics. Job #24315 Reopened 7/8/2025
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immunofluorescence, PhenoCycler/CODEX, imaging mass cytometry, MIBI) or with spatial transcriptomics. Experience with DNA barcoding, lineage tracing, CRISPR screens or other high-throughput perturbation approaches
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mammalian riboswitches and defining their biological functions. Research activities may include: Genetic manipulation of mammalian cell lines using CRISPR-based approaches Construction and analysis
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Palindromic Repeats (CRISPR)-based tools, and transposon mutagenesis. Experience with anaerobic microbiology techniques, including cultivation, handling, and experimental work under strictly anaerobic
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with human pluripotent stem cells, high throughput screening, genome editing (CRISPR/Cas9), rodent microsurgery, and bioinformatics datasets is a plus. Knowledge, Skills and Attitudes: Cell culture
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of DNAAF9 (axonemal dynein assembly factor 9) in ciliary biology. This will involve CRISPR genetic engineering using relevant ciliated cell lines to knockout DNAAF9 followed by cytological, proteomic and