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measures across multiple zebrafish models of leukodystrophy, including models of RNASET2 deficiency, adrenoleukodystrophy (ALD), Krabbe disease and metachromatic leukodystrophy (MLD). Zebrafish are widely
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immunomodulatory compound, you will determine how it reprograms host lipid pathways to boost immunity and eliminate infection. Using lipidomics, zebrafish models and clinical samples, this research will identify
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. In this project we will study the functions of the rare coding variants using zebrafish and compare the results with mouse models of equivalent mutations and human post-mortem brain tissue
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brain circuits, but the role of protein synthesis in this key developmental process is still poorly understood. Using zebrafish and mouse models, this project will compare ribosomes in progenitors and
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Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) | Portugal | 2 months ago
Mitigating the effects of stress in early-life stages of fish is a critical challenge for the aquaculture industry and biomedical research using zebrafish as an experimental model. In this regard
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PhD position in environmental toxicology and endocrine disruption: Focus on new endpoints in zebr...
-validate new endpoints in zebrafish sensitive to, or diagnostic of, endocrine disruption caused by chemicals. The expected tasks include exposure of zebrafish to suspected and known endocrine disruption
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mechanisms. The planned project will use a broad range of technologies, including genetics, imaging, biochemistry, molecular biology, enzymology, cell culture and experimental animal models (mice and zebrafish