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Field
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research programme. You’ll work with scientists across the project to analyse and integrate complex genomic, transcriptomic and epigenetic datasets, including bulk and single-cell RNA-seq, ATAC-seq, ChIP-seq
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reproducible bioinformatics workflows and computational tools to process, analyze, and interpret high-throughput sequencing data, including genomics, transcriptomics, metabarcoding, and metagenomics datasets
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neurons and breast cancer organoids, together with clinical tissue material, to investigate cancer-nerve contact sites using multiplexed immunofluorescence, single-cell and single-nucleus transcriptomics
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early metabolomic disruptions, followed by the genetic and biochemical dissection of the mechanisms underlying these alterations. The project takes advantage of recent transcriptomic and imaging data
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, pathways, and targets associated with Alzheimer's disease, Parkinson's Disease, and other neurological traits by performing deep molecular phenotyping (genetics, transcriptomics, proteomics, epigenomics
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molecular methods. • RNA-seq, transcriptomic analysis, or basic bioinformatics. About the Department Committed to innovation and diversity, the Medical School educates physicians, scientists, and health
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programme as well as other research collections, integrating findings with clinical data, epigenetic results, transcriptomics, and proteomics. They will work closely with other members of the MND research
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that leverage the immunosuppressive properties of Tregs. The successful candidate will provide lab-based functional validation of scRNA-seq and spatial transcriptomic findings, translating these into clinically
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-lacZ, promoter-gfp, and RT-qPCR assays; growth curve assays; biochemical colorimetric and fluorescence assays; PCR and Sanger sequencing experience; and familiarity with genomics and transcriptomics. Pay
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an ongoing collaboration between the Khmelinskii and Padeken groups, which gives you the opportunity to become an expert in a wide range of methods and experimental approaches. This includes transcriptomics