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that recapitulate glioblastoma infiltration of healthy brain tissue. Applicants with expertise in the culture and differentiation of human induced pluripotent stem cell (iPSC)-derived models, protein biochemistry
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pluripotent stem cell (iPSC)-derived models, protein biochemistry, molecular and cellular biology, and high-resolution confocal imaging are particularly encouraged to apply. The successful candidate will lead
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engineering, bioengineering, neuroscience, cell biology, electrical engineering, or a related field. Hands-on experience with mammalian cell culture, preferably neuronal or stem-cell-derived cultures
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Details Title Postdoctoral Fellow-Computational Biologist School Faculty of Arts and Sciences Department/Area Stem Cell and Regenerative Biology Position Description The Arlotta lab, in
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Parkinson’s disease. Central to this effort are CRISPR screens that identify genes that make neurons more vulnerable or resilient to stress. These screens will use human induced pluripotent stem cell (iPSC
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screening pipeline, from stem-cell engineering to data analysis Develop and test improvements in single-cell methods and vector design Apply the technology in steady-state and disease settings Analyse
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investigates the epigenetic regulation of normal and malignant hematopoiesis. The successful applicant will be responsible for characterizing the roles of various epigenetic modifications in stem cell
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regulator of cell differentiation and stemness. Aberrant differentiation leads to developmental defects and cancer. We hypothesize that aberrant differentiation that is perturbed by abnormal Wnt/β-catenin
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molecular structures during normal and leukemic stem cell differentiation. Integrated in the translational research environment at the Center for Hematology and Regenerative Medicine at the Karolinska
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Hematopoietic stem cells (HSCs) ensure the lifelong production of all blood cell types. With age, HSCs undergo functional and molecular changes that impair their regenerative capacity and contribute