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Parkinson’s disease. Central to this effort are CRISPR screens that identify genes that make neurons more vulnerable or resilient to stress. These screens will use human induced pluripotent stem cell (iPSC
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Details Title Postdoctoral Fellow-Computational Biologist School Faculty of Arts and Sciences Department/Area Stem Cell and Regenerative Biology Position Description The Arlotta lab, in
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investigates the epigenetic regulation of normal and malignant hematopoiesis. The successful applicant will be responsible for characterizing the roles of various epigenetic modifications in stem cell
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screening pipeline, from stem-cell engineering to data analysis Develop and test improvements in single-cell methods and vector design Apply the technology in steady-state and disease settings Analyse
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regulator of cell differentiation and stemness. Aberrant differentiation leads to developmental defects and cancer. We hypothesize that aberrant differentiation that is perturbed by abnormal Wnt/β-catenin
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will be given to candidates with translational research experience in cancer immunology, antibody-based therapeutics, and/or antibody/protein engineering; as well as cell/organoid culture, cellular
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Hematopoietic stem cells (HSCs) ensure the lifelong production of all blood cell types. With age, HSCs undergo functional and molecular changes that impair their regenerative capacity and contribute
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molecular structures during normal and leukemic stem cell differentiation. Integrated in the translational research environment at the Center for Hematology and Regenerative Medicine at the Karolinska
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University of California, Los Angeles | Los Angeles, California | United States | about 10 hours ago
employ cellular and molecular approaches, stem-cell-derived models, gene editing, and disease-relevant experimental systems to investigate vascular regulation of tissue repair and therapeutic regeneration
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Welcome to Maastricht University! We have developed a new class of oncology drugs that exploit the tumour microenvironment for selective activation that target the NOTCH stem-cell pathway in cancer