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neurodevelopmental disorders? This project will use human stem cells to grow early brain cells, then rapidly switch off selected disease-linked transcription factors. By measuring the immediate effects on chromatin
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cells including macrophages). - Modelling of CKD-like vascular injury in 3D vascular organoids derived from induced pluripotent stem cells (iPSCs), exposed to phosphate, uremic toxins and pro-inflammatory
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potential in vivo. The project requires a strong foundation in neuroscience and an interest in both stem cell-based and animal research. Prior experience with cell culture techniques, behavioural and
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the future of health and life sciences. By integrating stem cell biology, patient-derived material, tissue engineering, microfluidics, advanced analytics, and digital technologies, NAM platforms enable
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, Stem Cell Biology, Biotechnology, Biochemistry, or a closely related discipline. Candidates with experience in bioinformatics and omics data analysis are encouraged to apply. Required Related Experience
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expected to carry out advanced computational analyses. Our underlying model system is the in vitro differentiation of adipose tissue stem cells into adipocytes. The project is in collaboration with
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with experience but competitive. Type of Position Student Position Time Status Full-Time Required Education Ph.D. in Immunology, Cell Biology, Molecular Biology, Biomedical Sciences, Microbiology, Stem
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that clomipramine rescues the altered SMPD1 (acid sphingomyelinase) phenotype in SMA cellular models, including human induced pluripotent stem cell (iPSC)-derived motor neurons (Brokate et al., 2025). Since SMPD1
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the future of health and life sciences. By integrating stem cell biology, patient-derived material, tissue engineering, microfluidics, advanced analytics, and digital technologies, NAM platforms enable
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proliferating stem cells to differentiated and polyploid tissues. We investigate how DNA replication is dynamically regulated to preserve genome integrity while supporting development, tissue homeostasis and