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. You will use human in vitro models, including astrocytes and brain organoids generated from induced pluripotent stem cells (iPSCs) of people with MLC and healthy controls. You will investigate disease
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potential in vivo. The project requires a strong foundation in neuroscience and an interest in both stem cell-based and animal research. Prior experience with cell culture techniques, behavioural and
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two complementary backgrounds. You may have experience in iPSC-based disease modelling, stem-cell or cell biology and an interest in developing your data-analysis skills, or a background in
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stem cell-based and animal research. Prior experience with cell culture techniques, behavioural and neurological phenotyping, and handling mice is an advantage. Planned secondments will provide