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Field
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human to animal, employing novel imagining and electrophysiologic techniques, to name a few. The successful candidate will employ cell culture skills, cell imaging, and cell patch clamp techniques as
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proven experience in electrophysiology (patch-clamp) and/or ion imaging in heterologous expression systems and/or native cells (eg vascular) and/or live or immunostaining imaging of microvasculature in
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basis of memory. Expertise in patch clamp electrophysiology and recording techniques (ideally in brain slices) is essential and experience with 2-photon imaging is desirable. Experience with data handling
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microscopy, optogenetics, or in vivo imaging techniques. Experience with electrophysiological recording methods, including patch-clamp techniques. Programming and data analysis experience using MATLAB, Python
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main tasks will consist of: Independent research of high international quality, including publication. Conducting stereotaxic surgery with neonatal mice Conducting whole-cell patch clamp recordings In
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an interdisciplinary approach that integrates mitochondrial patch-clamp electrophysiology, advanced live-cell and label-free imaging, structural biology (cryo-electron tomography and cross-linking mass spectrometry
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an advantage. Experience with neuron-glioblastoma co-cultures, confocal microscopy, patch-clamp and animal handling and experimentation will be considered an advantage. The candidate should demonstrate
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electrophysiological (e.g., patch-clamp), imaging techniques, genetic mouse models (including CRISPR/cas9 technology), biochemical, and molecular approaches to investigate the regulation of signal transduction
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and objectives. Moreover, the Assistant Scientist, SOM contributes to the scientific community by publishing research findings and promotes the University’s reputation as a leader in the field. CORE JOB
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/10.1038/s41593-022-01094-6). Characterize light-gated ion channels (including KCRs and ACRs) using patch clamp electrophysiology in HEK293 cells and cultured neurons, assessing photocurrent amplitude