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, metabolomics, lipidomics, and other omics data to contextualize metabolic models and investigate complex biological questions. Interpret modeling and multi-omics results to identify biological mechanisms
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12 months, Fixed Term, whole-time Post Applications are invited for a Post-Doctoral Researcher to join a Research Ireland-funded project focused on characterising the gut bacterial lipidome
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; chemically constrained fragmentation spaces; explainable annotation of mass spectra; computational lipidomics; and algorithmic cheminformatics for mass spectrometry. The role requires the ability to connect
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samples, validated mouse models of hemorrhagic shock, a 3D endothelial flow model, and high-throughput proteomics, metabolomics, and lipidomics. Projects include therapeutic modulation of APC activity via
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an interdisciplinary research team Preferred Qualifications Experience analyzing metabolomics, proteomics, lipidomics, transcriptomics, or other high-dimensional molecular data Familiarity with methods such as dimension
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with metabolomics, lipidomics, proteomics, bioanalysis, natural products, or related mass spectrometry applications. Experience preparing biological samples for mass spectrometry-based analyses including
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screens Experience in the analysis and interpretation of biological datasets, particularly omics data (e.g., genomics, transcriptomics, lipidomics, and metabolomics) Knowledge of statistical data analysis
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microenvironment including genomics, transcriptomics, lipidomics, metabolomics Perform molecular techniques including DNA/RNA isolation, PCR, ddPCR, RNA-seq, ATAC-seq and DNA methylation. Develop and/or perform
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lipidome independently modulate translocase stability. This aim will be executed using the following biochemical techniques: In vitro import assays: Using radiolabeled precursor proteins in isolated
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biology experiments including flow cytometry, microscopy (standard imaging and FRET, FLIM, FRAP), proteomics, lipidomics and transcriptomics analyses. We are also expanding to iPSC-neurons and in vivo work