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has obtained a doctorate degree in Biological Sciences within the last 7 years and has a strong publication record. Experience in cell culture and neurodifferentiation is essential, while proficiency in
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), cryo-electron tomography in lamella (cryo-ET) and expansion microscopy (ExM), that can be also applied to other proteins in the lab. Methodological Responsibilities: 1) Sample Preparation: Engage in cell
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Validation of novel molecular targets from anti-inflammatory and cytoprotective molecules in neurons
targets through the investigation of anti-inflammatory peptides derived from animal venoms. The activities involve elucidating the peptide effects in cell culture, and in vivo using inflammatory and pain
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handling and crossing mice, cell culture, in vitro coculture assays, adoptive cell transfer, flow cytometry, cell isolation through cell sorting. ELISA and gene editing through CRISPR/Cas9. Interested
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crossing mice, cell culture, in vitro coculture assays, adoptive cell transfer, flow cytometry, cell isolation through cell sorting, ELISA and gene editing through CRISPR/Cas9. Interested parties should send
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comprehensive approach, which includes anatomical/structural analyzes, secondary cell wall characterization, phenolic profiling and saccharification assays. This is a “proof-of-concept” project to demonstrate
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Medical School (FMUSP) in São Paulo city, Brazil – is focused on the pathogenesis of Chagas disease cardiomyopathy (CCC), an endemic disease affecting millions of patients in Latin America. T cells from CCC
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, in addition to being related to the repair of inflammatory processes. Data demonstrated that osteopontin appears to regulate the T cell response, with inhibition of the anti-inflammatory cytokine IL-10
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pluripotent stem cells exposed to the serum of diabetic patients with coronary artery disease before and after treatment with empagliflozin. Candidates with experience in cell culture, intracellular Ca2
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. The project envisages carrying out cell cultures and brain organoids in infection experiments with infectious clones of luminescent or fluorescent ZIKV or SARS-CoV-2. Analyses of the interaction of these viral