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microenvironment, and other hematological and solid neoplasms. Such models incorporate multi-omics high-throughput assays such as RNA-seq, ChIP-seq, ATAC-seq, MPRA, PC-HiC. Participates in the configuration and
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The Borkar lab focusses on high-resolution investigation of RNA mediated disease pathologies during viral infection and rare genetic disorders. We are looking for an experienced postdoctoral
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at the postdoctoral level to join our team. The primary responsibilities include bioinformatics analyses (including integration of multiple dataset) with a strong focus on single-cell RNA and ATAC sequencing and
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quantification · Tissue and cell extraction of RNA/DNA and protein · Proficiency in Western blot assay, PCR, immunohistochemistry · Mouse handling and survival surgery · Aseptic
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-mediated changes to RNA binding proteins in the context of paediatric high-grade gliomas. The successful candidate will manage their own research and administrative activities, adapt existing and develop new
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, RNA extraction/ preparation, and quantitative PCR. Prepare general laboratory reagents, buffers, and media; assist in maintaining laboratory stock and monitoring inventory Draft, update and organize
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flow cytometry, mass cytometry (CyTOF), single-cell RNA sequencing, and T-cell receptor (TCR) repertoire analyses. Analyze complex immunological datasets using FlowJo, R, RStudio, and other statistical
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-resolution microscopy, single-cell RNA sequencing (scRNA-seq), and spatial transcriptomics. • Scientific Leadership: Independently manage project milestones, draft high-impact manuscripts, present findings
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. Experimental approaches will include primary human cell culture, ELISA, ELISPOT, protein assays, RNA-seq, single-cell genomic approaches, and functional cell-based assays. The applicant will also be involved in
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) biology and osteoarthritis - Mouse genetic models and lineage tracing - Single-cell RNA sequencing and spatial transcriptomics - Skeletal mechanobiology and functional loading models - Gene therapy and