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- Aalborg University
- ; UK Health Security Agency (UKHSA)
- Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento _IST-ID
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production changes, thanks to metabolic collaboration and flexibility, which improves the overall efficiency of the biorefinery process. Elemental analyzer, NMR, GC, and LC-MS etc. will be used to characterize
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coupled with parallel identification of particle chemical composition using LC and GC-MS methods among others, the project will determine the relative toxicity of tyre wear particle types. Ultimately
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the statistical design of experiments, the analysis of the fermented materials by physico-chemical methods(LC-MS, NMR) and specific functional assays, as well as the assessment of the beneficial effect
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on the biophysical modulation and proteomic analysis of mitochondria in relation to the maintenance of myocardial function. Keywords: heart mitochondria, cardioprotection, proteomic, LC-MS Supervisor: Ing. Miroslav
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LC/MS, MALDI imaging, NMR spectroscopy and different types of chromatography. Isolation and structural elucidation of unknown and/or bioactive secondary metabolites, e.g. antifungals from microbes
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actinobacteria (Streptomyces). Your methodological focus will be on molecular microbiology, next-generation sequencing (NGS, RNA-seq and ChIP-seq), LC-MS/MS, and fluorescence microscopy. Please find further
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well as the identification of biomarkers with predictive, prognostic and diagnostic value. We are currently engaged in multiple method development projects including deep proteomics (HiRIEF-LC-MS), proteogenomics, post
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spectrometry, and Nuclear magnetic resonance), and/or molecular biology (cloning, PCR, protein expression, SDS-PAGE, CRISPR/CAS9). Experience in LC-MS analysis of microbial crude extracts, bioinformatic analysis
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diagnostic value. We are currently engaged in multiple method development projects including deep proteomics (HiRIEF-LC-MS), proteogenomics, post-translational modification analysis as well as subcellular
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biological samples using LC-MS; use bioinformatics tools to integrate the data with proteomics and transcriptomics analyses Collaborate with clinical scientists and analytics specialists to identify and