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Primary Supervisor: Dr Ke Li Foundation models trained on DNA and RNA sequences are beginning to transform genomics, but their predictions often remain difficult to interpret. A model may identify a
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circulating tumor DNA, with comprehensive tissue-based profiling methods such as gene expression analysis, DNA sequencing, single-cell sequencing, and spatial transcriptomics. These high-dimensional data
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, PacBio HiFi long-read genomic sequencing, comparative and population genomics, and bioinformatics. TRAINING AND COLLABORATIONS: The successful candidate will join a multidisciplinary research environment
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on single-cell and spatial genomics data, from sequencing and imaging, and apply them to human developmental and disease biology. Possible research directions include: ● Generative models of cell–cell
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variation as an anchor for causal inference across molecular layers (genomics, transcriptomics, proteomics, and metabolomics), enabling more principled identification of disease-relevant proteins and pathways
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genome sequencing and single-cell approaches, as well as broader data integration across multiple omics data types. The role holder will apply their computational and bioinformatics skills to contribute
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German Cancer Research Center in the Helmholtz Association (DKFZ) | Heidelberg, Baden W rttemberg | Germany | 3 months ago
environment is highly collaborative and interdisciplinary, spanning genome biology, computational analysis, and translational cancer research. Members of the lab gain expertise in next-generation sequencing
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will apply a broad spectrum of state-of-the-art techniques, including: microbial isolation and culturing, plant infection assays, microbiome sequencing and analysis, whole genome sequencing, comparative
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to characterize this phenomenon at single-cell resolution using whole-genome sequencing and artificial intelligence (AI)? If so, this PhD position could be an excellent fit for you! In this ZonMw-funded project
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? Do you want to develop your skills to characterize this phenomenon at single-cell resolution using whole-genome sequencing and artificial intelligence (AI)? If so, this PhD position could be