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at NIOO-KNAW), with genomic and epigenomic editing that identifies genes regulated by DNA methylation and tests the causal effects of candidate epialleles on gene expression (PhD project at UU). What you
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to characterize this phenomenon at single-cell resolution using whole-genome sequencing and artificial intelligence (AI)? If so, this PhD position could be an excellent fit for you! In this ZonMw-funded project
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? Do you want to develop your skills to characterize this phenomenon at single-cell resolution using whole-genome sequencing and artificial intelligence (AI)? If so, this PhD position could be
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to profile tumour and immune cells in melanoma organoid co-cultures and live tissue slices. At Erasmus MC, the candidate will work to combine spatial FUNseq with single-cell genome and transcriptome sequencing
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, and gene expression variation between apomictic plants, which exposes putative natural epialleles (PhD project at NIOO-KNAW), with genomic and epigenomic editing that identifies genes regulated by DNA
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plasma and iPSC-derived human disease models. You will investigate disease-related molecular signatures using metabolomics, lipidomics, proteomics and genomics, and combine these data using statistical and
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state-of-the-art single-cell RNA sequencing (scRNA-seq) alongside bulk and single-cell epigenomic assays. o Data Integration: Collaborating with data scientists to map molecular signatures to clinical
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renowned virologist and one of the pioneers of the CRISPR-Cas technology, which works by cutting a DNA sequence at a specific genome location and deleting or inserting genes there. The CRISPR-Cas method