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Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt | Germany | 3 months ago
biology and organismal biology, including animal models is essential. Previous hands-on experience in molecular biology and biochemistry including protein, RNA and DNA isolation from tissues and CRISPR-Cas9
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samples obtained from in vivo cancer models (in conjunction with the Thomsen group and Histocore) and establishing explant/tissue slice cultures. Engineering cell lines and in vivo models using CRISPR and
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), inflammatory bowel disease (IBD), and/or experimental autoimmune encephalomyelitis (EAE). Using unbiased genome-wide CRISPR/Cas9 guide RNA library screens and whole kinome analyses, we have identified promising
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gain experience in pooled screening techniques including library cloning, CRISPR screening, protein purification, proteomics and sequencing. We will use Python and Bash scripting to analyze and visualize
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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homeostasis. The Wang group has been using Cre-loxP/Flp-frt and CRISPR strategy to manipulate genes of interest and use chemogenetics/optogenetics strategy to manipulate neuronal activities in specific neuron
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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signaling, and GPCR or kinase biology is essential. Experience in at least two of the following—mammalian cell culture and iPSC differentiation, site-specific genome integration and CRISPR/Cas9 gene editing
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything