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Field
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the presence of a cancer cell immobilized on the chip by quantum-tunneling current fluctuations. Experimental studies are complemented by two key theoretical and computer modeling pillars: extensive all-atom
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The Department of Molecular and Cellular Oncology (MCO) advances basic, translational and clinical efforts to make MD Anderson the number one cancer research center. The department's oncology-driven
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”. They showed that the tumor microenvironment enforces the production of aberrant proteins in cancer cells (Bartok et al., Nature 2021; Champagne et al., Molecular Cell 2022; Pataskar et al., Nature 2022; Yang
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system. It is these same detectors, in particular the protein called cGAS, which will recognize the cytosolic DNA of cancer cells and, after STING protein activation, alert the immune cells. But how can we
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biologists, physicists and chemists in industry and academia? Are you interested in developing a new set of tools that can be used to image metals, metabolites and proteins in cells at unprecedented spatial
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), College of Medicine, Department of Surgery, is accepting applications for a highly motivated full-time Research Assistant Professor with experience in cancer and molecular biology join the team of an NIH
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human proteome analysis. We develop innovative methods to enhance personalized cancer treatments. Proteomics is the large-scale study of proteomes - entire sets of proteins in a biological system. This
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, nutritional, physical or chemical stress, by eliminating non-essential or damaged proteins and cellular organelles. Autophagy is also involved in many developmental processes and during aging, and its
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Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Thus, a major problem in life-sciences research is to understand and manipulate PPIs with
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, bioinformatics, cancer precision medicine, proteogenomics and network analysis to develop methods that transition analysis from cohort-level to patient-specific protein-protein interaction networks, using in-house