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Field
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possible hereafter. Our group and research Kummer group investigates protein complexes that help to maintain and express mitochondrial as well as viral DNA. Here, we are specifically interested in
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, nutritional, physical or chemical stress, by eliminating non-essential or damaged proteins and cellular organelles. Autophagy is also involved in many developmental processes and during aging, and its
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Transient protein-protein interactions (PPIs) control all cellular processes relevant to health and disease. Thus, a major problem in life-sciences research is to understand and manipulate PPIs with
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, bioinformatics, cancer precision medicine, proteogenomics and network analysis to develop methods that transition analysis from cohort-level to patient-specific protein-protein interaction networks, using in-house
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Primary supervisor - Dr Amit Sachdeva Secondary supervisor - Prof Andy Cammidge Over the last decade, several antibody-based biotherapeutics have been developed for treatment of cancer
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protein homeostasis which are important for a number of aging-related diseases, including neurodegeneration, and several forms of cancer. The research group of Professor Christian Kaiser , which just
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interventions against protein misfolding and perturbed protein homeostasis which are important for a number of aging-related diseases, including neurodegeneration, and several forms of cancer. The research group
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proteins in cancer and how protein misfolding and aggregation result in amyloids. Recent results have shown that amyloids formed by the protein alpha-synuclein, which is linked to Parkinson's disease, can
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Cancer Institute in Amsterdam has recently uncovered a novel phenomenon in cancer termed “Sloppiness”. They showed that the tumor microenvironment enforces the production of aberrant proteins in cancer
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detail, you will contribute to a further understanding of the role of DNA repair and metabolisms proteins in cancer and characterize small molecules inhibiting these pathways and proteins involved using