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Field
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programme as well as other research collections, integrating findings with clinical data, epigenetic results, transcriptomics, and proteomics. They will work closely with other members of the MND research
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that leverage the immunosuppressive properties of Tregs. The successful candidate will provide lab-based functional validation of scRNA-seq and spatial transcriptomic findings, translating these into clinically
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-lacZ, promoter-gfp, and RT-qPCR assays; growth curve assays; biochemical colorimetric and fluorescence assays; PCR and Sanger sequencing experience; and familiarity with genomics and transcriptomics. Pay
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an ongoing collaboration between the Khmelinskii and Padeken groups, which gives you the opportunity to become an expert in a wide range of methods and experimental approaches. This includes transcriptomics
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, including scRNA-seq, spatial transcriptomics, methylation profiling and integration of molecular data. Experience in translational biomarkers, target-engagement studies (PD), analysis of human biological
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for a research grant within the framework of project “ST-e.Biofilm – Development of spatial transcriptomic for the characterization of engineered biofilms”, with operation code at Funds Platform (Balcão
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health challenges. This position is for a full-time Research Assistant in the Ho Laboratory led by Jessica S. Ho in EID. Viruses dramatically alter the transcriptomes and the epigenomes of their host cells
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, including analysis of genomic/metagenomic/transcriptomic data, would be an advantage. Experience with R, Python, Linux/Unix, sequence-analysis tools, or biological databases is an advantage. Good analytical
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with hallmark PD pathology, using machine-learning approaches to quantify neuroinflammatory and protein pathologies and spatial transcriptomics to characterise their molecular and spatial relationships
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involving tissue microarrays. F2 Technical experience in aspects of spatial biology, such as multiplex phenotyping, next generation sequencing methodologies, spatial transcriptomic analysis. F3 Data analysis