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Field
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explores genetic causes of neurological disorders and aim to develop therapies for these conditions with a high complementary approach, ranging from stem cell modelling to functional genomic. Information
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) mediate differentiation of induced pluripotent stem cells into cardiovascular lineages, and 2) biomaterials that mediate transdifferentiation of somatic cells into cardiovascular lineage. In particular, we
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peripheral blood stem cell transplantation and tumor models. Studies may also include use of human cells and humanized NSG mouse models. Ongoing research includes novel approaches in activating anti-tumor
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validate innovative electroactive biomaterials and bioelectronic devices that promote cardiac regeneration by combining tissue engineering, biomaterials, stem cell biology and bioelectronics. Working closely
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system (CNS). We aim to uncover the principles of cell fate regulation during development and repurpose them for regeneration. We use a multidisciplinary approach that involves glial and stem cell biology
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microscopy and imaging approaches Hands-on experience with genome editing technologies (CRISPR-based techniques) Hands-on experience with cellular differentiation systems, stem cell biology and cellular models
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culture of mouse oocytes and embryos; experience with isolation and culture of embryonic stem cells; experience with immunofluorescence and confocal microscopy; experience with molecular cloning and next
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researchers with diverse skill sets and a common interest in elucidating the extrinsic and intrinsic signals that regulate stem cell behaviour. The Spagnoli lab is a highly dynamic team, doing exciting science
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differentiation of pluripotent stem cells into retinal cells and tissues. The work will specifically employ scalable culture modalities and bioreactors. This work will be undertaken in close collaboration with
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/PhD degree with a focus on Metabolism, Mouse Models systems, Human stem cell systems, Biochemical and Molecular Tools, Epigenetics, Genetics, Genomics, Biology, Bioinformatics, Machine Learning, or a