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that clomipramine rescues the altered SMPD1 (acid sphingomyelinase) phenotype in SMA cellular models, including human induced pluripotent stem cell (iPSC)-derived motor neurons (Brokate et al., 2025). Since SMPD1
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two complementary backgrounds. You may have experience in iPSC-based disease modelling, stem-cell or cell biology and an interest in developing your data-analysis skills, or a background in
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stem cell-based and animal research. Prior experience with cell culture techniques, behavioural and neurological phenotyping, and handling mice is an advantage. Planned secondments will provide
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funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description PhD position: How Cells Scale
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within the chair Cell and Developmental Biology , which is led by Prof. Viola Willemsen. You will work together with a technician in the Stem cell specification and Regeneration team and be supervised by
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the axons from retinal ganglion cells (RGCs) that transmit visual information from the eye to the brain. This PhD project aims to address this challenge by identifying novel regenerative therapies capable
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, neurodegeneration, advanced microscopy, stem cell biology, and cell biology. The project will leverage state-of-the-art imaging facilities and established human iPSC-derived models of Alzheimer's disease. The work is
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24 Aug 2026 Job Information Organisation/Company Hector Fellow Academy Research Field Engineering Medical sciences Technology Researcher Profile First Stage Researcher (R1) Positions PhD Positions
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neural stem cell (NSC) niche. Recent studies have revealed key aspects of human rhombic lip (hRL) organization and shown that defects in its development underlie several human syndromes. These findings
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-on-brain.eu/ ). You will employ techniques such as organoid cultures (pluripotent stem cell and tissue-derived), transcriptomic analyses, CRISPR-Cas engineering, and other state-of-the-art tools. Your