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Field
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, regioselectivity and stereoselectivity in complex carbohydrate substrates. Purify products and intermediates using flash chromatography, preparative HPLC, recrystallization and other suitable methods. Job
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-payloads and ADCs using flash chromatography, preparative HPLC, SEC/FPLC and other suitable methods. Characterize products and assess identity, purity, drug-to-antibody ratio and aggregation using NMR, LC-MS
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of linkers, fluorophores, chelators and other functional groups. ● Purification and analytical characterization using HPLC, LC-MS and related approaches. ● Systematic structure-function studies
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, integrating, applying and sharing knowledge directly related to a professional field. Key Responsibilities / Duties: Independently set up HPLC mass spectrometry equipment for analysis. Independently develop and
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, HIC, SEC, RP-HPLC), Tangential Flow Filtration and other filtration techniques. Single-domain antibody generation and characterization (including library generation, phage display, SPR, ELISA, stability
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across core instrumentation such as FPLC, HPLC, LC‑MS, and SPR systems. This work ensures that IPD scientists can generate high‑quality and reproducible data and builds long‑term technical capacity
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equipped with everything necessary for the successful completion of the proposed research. Some equipment has been recently renewed: 600 MHz NMR (2026), HRMS (2026), chiral HPLC (2026); other equipment will
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, HPLC, and NMR - Development of an automated synthesis system - Writing reports and publications This recruitment is part of the PEPR moleculArXiv project, which aims to prepare macromolecules containing
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, LC-MS and HPLC analysis Experience with X-ray crystallographic analysis and protein structure determination or single particle cryo-electron microscopy structure determination and analysis Familiarity
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analytical techniques (HPLC, LC-MS, and GC), as well as computational tools. An integral part of the work will be the integration of biological data with medicinal chemistry principles to identify the most