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, electrical polarisation and, then evaluate cell-matrix interactions using live-cell imaging, molecular assays and, spatial transcriptomic approaches to identify key mechanisms linking matrix mechanics
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nanotechnologies, immunohistology, transcriptomics, antibody assays, and advanced 3D microscopy. For this, a lightsheet microscope dedicated to the imaging of cleared samples is being acquired, as well as a
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, transfection/transduction, and CRISPR-Cas9 approaches; contribute to experimental design and interpretation; help develop new 2D/3D cell and extracellular matrix assays; coordinate complex experiments across
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and 3D imaging methods for understanding metastasis and tumor deposit formation in colorectal tumors. Specifically, the work will focus on optimizing 3D X-ray virtual histology methods by phase-contrast
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, and transcytosis in the context of malaria immunology. Develop and optimize 2D and 3D endothelial-based assays to evaluate molecular modifiers of IgG handling and to investigate mechanisms
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estimation of 3D coronary hemodynamics (velocity, pressure, and wall shear stress fields); design computational pipelines that integrate image-based anatomy, blood flow physics, and uncertainty quantification
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of wildtype and Bdf1-mutant C. albicans strains. The project will also involve developing high-resolution 3D X-ray imaging approaches to investigate morphotype-dependent changes in the nuclear and subcellular
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diffraction imaging modalities - topotomography, dark-field X-ray microscopy, and Bragg coherent diffraction imaging - has emerged over the past decade that can resolve 3D defect architectures and strain fields
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desire to learn new (technical) skills; and proficiency with Python, Javascript, XML, CSS, and LaTeX. PREFERRED: Experience creating plots and 3D interactive images in Mathematica, MATLAB, or python; ties
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and analysis of soil and vegetation characteristics Participate in drone surveys and process and analyze 3D data Collect and analyze dust samples (MWAC samplers) Maintain automated erosion and