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(ustekinumab), and the JAK-STAT pathway (tofacitinib and upadacitinib), or molecules involved in immune cell recruitment to the gastrointestinal tract, such as integrin α4β7 (vedolizumab). Despite
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applicants for a PhD position in Stem cells and Multiple Sclerosis (MS). Your work will focus on human iPSC-based models of inflammation and MS to study microglial cell functioning in a white matter- and grey
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staff position within a Research Infrastructure? No Offer Description Diffuse Large B cell Lymphoma (DLBCL) is the most common aggressive (fast-growing) Non-Hodgkin-lymphoma with heterogeneous clinical
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Alzheimer’s disease such as ApoE4. In this PhD project, you will apply this previous knowledge to develop cellular screening assays in order to identify novel candidate interventions for Alzheimer’s disease
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sequencing protocols and computational tools to analyze cell-free RNA and DNA in the blood of patients. In this project we aim, together with lab-on a chip and gene-editing experts from the Universities
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on the cytokine responses of macrophages; Next to cell culture experiments, you will use and analyze state-of-the-art approaches such as RNA-sequencing and ChIP-sequencing analysis; Translate your findings
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for a highly motivated and enthusiastic PhD student with: An completed MSc in a relevant field; Preferably a background in stem cell biology and molecular biology. Experience with retinal or relevant
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of macrophages; Next to cell culture experiments, you will use and analyze state-of-the-art approaches such as RNA-sequencing and ChIP-sequencing analysis; Translate your findings to disease models; Align
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complications. While cell death and necrotic core formation associate with plaque instability and poor clinical outcome, fibrous-cap formation and thickening is associated with increased plaque stability in
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including machine learning gradient boosting / randomized tree approaches. Requirements Specific Requirements University degree; Finished a PhD; Hands-on experience with bioinformatic analyses (single cell