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researchers (https://www.ibs.fr/ fr/research/membrane-proteins-and-glycobiology/membrane-transport-group-h-nury/moreau-team/). The successful candidate will have access to the numerous facilities within and
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collaboration between the Molecular Biosensing and the Protein Engineering research groups at TU/e (see www.tue.nl/mbx and https://merkxlab.nl/ ). Their fields of expertise on continuous biosensing and protein
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; Supervisor: Prof. Ora Schueler-Furman; Length: 3 months. Purpose: Modeling of protein/protein interactions to facilitate constructions of BRET-biosensors. Website for additional job details https://phd
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(Germany) Project Title: Semi-synthesis of site-specifically modified β-catenin protein variants Objectives: 1. Generate unique labeled β-catenin variants for binding assays. 2. Explore the dynamics of β
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variation as an anchor for causal inference across molecular layers (genomics, transcriptomics, proteomics, and metabolomics), enabling more principled identification of disease-relevant proteins and pathways
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to measure intracellular protein-protein interactions in the Wnt pathway Investigate the impact of developed peptidic ligands on Wnt/β-catenin signalling and differentiation in C2C12 cells Measure: cellular
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, and Jeffrey H. Chuang. 2012. “Transcriptional Enhancers in Protein-Coding Exons of Vertebrate Developmental Genes.” PloS One 7 (5): e35202. https://doi.org/10.1371/journal.pone.0035202 . Although cis
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Khmelinskii in collaboration with Jan Padeken offers the following PhD project: The progressive deterioration of protein homeostasis (proteostasis) is a primary hallmark of aging. As organisms age, the
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to develop a protein purification facility. The IBGC operates under the supervision of the CNRS (INSB) and the University of Bordeaux. Its activities are dedicated to fundamental research in biology. The unit
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extracellular contractile protein translocation nanomachines. Importantly, the unique mode of action of T6SS allows bacteria to deliver folded proteins across membranes of neighboring bacterial or eukaryotic