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sequence the complete DNA of babies at birth to screen for hundreds of genetic conditions. This PhD project will generate the evidence to inform which genes and variants should be included in newborn genome
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research team of Dr Sarra Ryan in the use of ultra-long-reads and hybrid sequencing approaches to explore highly repetitive DNA sequence in relation to genomic instability in childhood cancer. Highly
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, CRISPR-Cas9, single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing (RNA-seq), multispectral imaging, immunohistochemistry, Western blotting, tissue culture, genotyping, and qPCR. Under
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flexibility as well as a strong motivation to address this challenge using multiple lines of evidence. Tasks and responsibilities: Co-designing and conducting field sampling and measurements, lab experiments
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. Experience working with geospatial data and spatial analysis, or the ability to learn. Experience analysing whole genome libraries, including quality control, sequence alignment, and calculating population
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About the position The exact tasks will depend on the skillset of the researcher and desired employment duration, but will include anaerobic cultivation of bacteria, single cell RNA sequencing, and
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of genomics such as genome sequencing and single cell approaches, in addition to broader data integration efforts across multiple types of 'omics data. The advertised role provides analytical support in
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genome sequencing and single-cell approaches, as well as broader data integration across multiple omics data types. The role holder will apply their computational and bioinformatics skills to contribute
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-groups/wang-group/ In the Wang Group, we develop and apply interdisciplinary technologies that bridge high-resolution spatial biology and genome-wide discovery. By integrating multi-omic sequencing and
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Your position You will develop generative models on single-cell and spatial genomics data, from sequencing and imaging, and apply them to human developmental and disease biology. Possible research