PhD position (m/f/d) Microbeam Radiation Therapy and FLASH

14.07.2022, Wissenschaftliches Personal [ACHTUNG: im Moment schreibend nicht nutzbar 27.08.2022]

The Department of Radiation Oncology, headed by Prof. Stephanie E. Combs offers a DFG funded PhD student (m/f/d) Radiation Oncology for the Analysis of the mechanism of Microbeam Radiation Therapy (MRT) and FLASH Therapy with a focus of radio-immune synergies. We are deploying syngeneic lung tumour and glioblastoma models to study the impact of an innovative irradiation therapy, called Microbeam Radiation Therapy (MRT) at a radiation source developed within an Emmy Noether project. This novel, still preclinical approach for cancer treatment uses micrometer sized x-ray treatment fields instead of broadbeam irradiation. The advertised project focuses on unravelling the beneficial effect of MRT on normal tissue while effectively controlling the tumour.

Your responsibilities:
- Perform experiments with murine syngeneic tumour models, carry out innovative tissue clearing methods and 3D histological analysis
- Analyse blood and tissue samples for potential inflammatory and immune reactions
- Measure abscopal effects after MRT/FLASH and investigate combinations of MRT/FLASH with immune-therapy
- Test hypotheses for potential mechanisms experimentally
- Perform experiments at an experimental source for MRT at MRI/TUM and at the European Synchrotron in Grenoble (France)

Your profile:
- You are a highly qualified and motivated student holding a (or being close to obtaining) M.Sc. or equivalent degree in biology, molecular biology or related fields
- Willingness to get involved into in vivo experiments with mice
- Due to the interdisciplinary framework and close collaboration with other scientists, very strong communicative skills are essential
- Highly proficient in spoken and written English
- Flexibility and mobility to make use of the scientific potential at the locations of the TUM (Klinikum rechts der Isar, Forschungscampus Garching) and of the Helmholtz Centre Munich

We offer you:
- Interaction within a multidisciplinary environment of biologists, physicists and clinicians
- A varied and professionally demanding position in a state-of-the-art working environment
- Comprehensive on-the-job training provided by experienced and qualified colleagues
- The opportunity to take part in internal and external professional development courses
- Performance-related salary in accordance with the TV-L public-sector salary scale plus attractive benefits offered to public- sector employees

We look forward to your application!

Please submit your complete application documents (including CV, cover letter, certificates and the expected availability date) by e-mail quoting number 07_026 by August 31st at the latest.

Dr. Stefan Bartzsch
Department of Radiation Oncology
Klinikum rechts der Isar der Technischen Universität München
Ismaninger Straße 22
81675 München

E-Mail Referentin: [email protected]

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Kontakt: [email protected]