PhD Candidate (m/f/d) Spatial Lipidomics and Structure Elucidation

The Leibniz-Institut für Analytische Wissenschaften - ISAS - e. V. develops efficient analytical methods for health research. Thus, it contributes to the improvement of the prevention, early diagnosis, and therapy of diseases like cardiovascular diseases, autoimmune diseases or cancer. Overall, the institute strives to advance precision medicine by combining knowledge from different fields such as biology, chemistry, pharmacology, physics, and computer science. ISAS is a member of the Leibniz Association and is publicly funded by the Federal Republic of Germany and its federal states.

At our location in Dortmund we invite applications for a

for a DFG-funded project. This project will aim to structurally and spatially resolve the altered lipid metabolism in cancerous tissue by mass spectrometric means.

You will be responsible for

• Studying lipid alterations in cancer tissue by mass spectrometry imaging.
• Testing and developing novel sample preparation strategies as well as matrix materials for mass spectrometry imaging of tissue sections.
• Structure elucidation of phospholipids in cancerous tissues
• Collaborative research with medical science researchers
• Data analysis of large spatially resolved lipidomics data sets

Your profile

• Masters, Diploma or equivalent degree in Organic Chemistry, Analytical Chemistry, Biochemistry or related subjects
• Good understanding of Analytical Chemistry of MALDI MS and ESI MS
• Good skills in organic synthesis and derivatization are beneficial
• Basic understanding of lipid metabolism is preferable
• Experience with mass spectrometric equipment is beneficial

We offer

• A clear research topic as well as multifold training and support for PhD students in framework of ISAS and the Leibniz association
• Training and scientific development opportunities in an international environment and an excellent working atmosphere in a very dynamic and professional team
• Extensive state-of-the-art equipment and infrastructure in various analytical methods
• The opportunity to present your data on international conferences and participate in workshops

Non-residents who apply for this job will receive help from the institute to find accommodation and to handle authorities. Applications from disabled applicants are welcome. ISAS supports the principle of equal opportunity for all employees and therefore particularly encourages women to apply.

The salary will be according to the German TV-L. The part-time position (65%) is offered for three years. The position is available immediately. The time limitation of the contract is based on the Wissenschaftszeitvertragsgesetz (WissZeitVG).

ISAS collects and processes the personal data of its applicants in accordance with European and German legal regulations. Further information on data protection and the processing of personal data can be found at www.isas.de/datenschutzhinweise-fuer-bewerberinnen-und-bewerber .

The closing date for applications is April 25, 2024. Please apply via our applicant portal . Informal requests (reference number 299_2024) are welcome and can be directed to the Human Resources team (bewerbungen(at)isas.de ). Further information about the institute can be found at: http://www.isas.de/en .