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approaches to investigate tumour heterogeneity in melanoma. The successful candidate will develop and optimize a comprehensive workflow that integrates spatial transcriptomics, proteomics, and lipidomics
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CRISPR-mediated genetic engineering and pharmacological perturbation approaches. Multi-omics integration (lipidomics, metabolomics, proteomics and transcriptomics) will be used to identify pathogenic
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COMET-based spatial proteomics. This project is carried out in strong collaboration with academia/industry partners with visits to their laboratories expected: During a first secondment at AtlasXomics (3
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iteratively refined by converging evidence from downstream validation (such as chemo-genetics, structural modelling, functional assays, thermal proteome profiling and omni-omics), creating an adaptive and