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Field
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fully funded Postdoctoral position to study Alzheimer’s disease and other neurodegenerative disease proteomics signatures. The Cruchaga lab generates and analyzes high-throughput multi-omic data to study
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clinical development. You will use quantitative proteomics to define how mutations and inhibitors alter Rab GTPase phosphorylation and lysosomal signalling, and to identify biomarkers of pathway activity in
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Chemistry, Chemical Biology or Biochemistry (or be close to completion), together with: practical experience with common fragmentation approaches utilised in the field of proteomics; the ability to carry out
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-seq, single-cell RNA-seq, proteomics, metabolomics, ATAC-seq, ChIP-seq, spatial transcriptomics, spatial proteomics, spatial metabolomics and imaging mass cytometry (CyTOF). A major emphasis will be
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, demonstrable experience in mass spectrometry-based proteomic analysis or in RNA sequencing, as well as a background in immunology and biochemistry; - Experience in quantitative proteomics data analysis and de
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fragmentation approaches utilised in the field of proteomics; the ability to carry out analytical procedures that are applied for proteome characterisation to a high degree of precision; able to analyse
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position within a Research Infrastructure? No Offer Description Activities and context The successful candidate will join a multidisciplinary project spanning immunology, oncology, proteomics, genomics
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perform phenotyping. In addition, you will utilize mass spectrometry (metabolomics, proteomics, chemical biology) to define metabolic targets. You will be the primary driver of the project, working
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NIH awards is available in the The Peng Lab (Department of Ophthalmology, UCLA). Our laboratory combines single-cell multiomics (scRNA-seq, scATAC-seq, spatial transcriptomics), cell-surface proteomics
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glucose signaling and molecular changes contribute to cognitive decline during aging and risk for Alzheimer’s disease. The researcher will combine proteomics with fiber photometry measurements of glucose