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allosteric coupling, to exquisitely control signal routing. We integrate structural biology (NMR, X-ray, cryoEM) and biophysical techniques (FRET, ITC, BLI) with cellular readouts (TopFlash, BRET) and
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the most attractive university in the Czech Republic with ten faculties, more than 7 000 staff and 33 000 students, a wide range of research areas and a strong international position. We are the largest
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