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(pharmacokinetics, PK) and drug effects (pharmacodynamics, PD) is often poorly understood. This PhD project aims to improve our understanding of how commonly used medication affects critically ill
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Early Development Medical Directors (EDMD). CP provides pharmacokinetic (PK) and pharmacodynamic (PD) expertise. M&S provides model-driven PK and PK/PD quantitative pharmacology expertise. EDMD leads
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implementing model-informed drug development (MIDD) strategies, including population PK/PD, exposure–response, and mechanistic systems modeling approaches. They will collaborate closely with cross-functional
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support project leads at Moderna by evaluating and implementing model-informed drug development (MIDD) strategies, including population PK/PD, exposure-response, and mechanistic systems modeling approaches
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to improved clinical outcomes. By leveraging innovative pharmacokinetic (PK) and pharmacodynamic (PD) methods, the postdoc will integrate clinical pharmacology with advanced -omics analysis
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disease state affect the pharmacokinetics and pharmacodynamics (PK-PD) of drugs. To this end, you will develop and apply pharmacokinetic-pharmacodynamic models, informed by in vitro and/or clinical
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 14 hours ago
pharmacokinetic/pharmacodynamic (PK/PD) modeling or systems pharmacology is highly desirable. - Familiarity with regulatory science or clinical trial data is a plus. Preferred Qualifications
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therapeutics as well as pharmacokinetics (PK) and pharmacodynamic (PD) properties that give insights into what the body does to the drug (PK) and what the drug does to the body (PD). The program also has a
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experience advancing novel therapeutic programmes through preclinical development. You will bring expertise across areas including assay and translational strategy, biodistribution and PK/PD, safety and
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therapeutic care by developing and applying pharmacometric (i.e. PK, PD, disease) mathematical & statistical models. We are currently inviting applications to enrol in the PharMetrX Research+ Program or the