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sample, and in vivo leukemia models Perform and oversee molecular, cellular, genomic, and functional assays Analyze, interpret, and integrate multi-omics datasets to generate biologically meaningful
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cells. Compounds identified through a pharmacological screening approach represent promising therapeutic leads, including in models of bortezomib-resistant cell lines. The project combines a fundamental
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interpretable models that connect molecular patterns across multiple scales of human biology. The project lies at the interface of artificial intelligence, computational biology, systems medicine, and precision
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production provides a competitive advantage to commensal bacteria, thereby limiting the establishment of pathogenic strains. This work adopts a multidisciplinary approach, combining methods from molecular
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activity in vitro; basic knowledge of bioinformatics, molecular modelling and docking and/or structural analysis of protein–ligand complexes, as well as the ability to use in silico results to guide
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postdoctoral position is available in the laboratory of Prof. Alex Persat (EPFL School of Life Sciences, https://www.p-lab.science/ ) to establish a new image-based drug screening platform targeting gram
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of Duties Explore molecular mechanisms linking to cancer, obesity, liver, women diseases using a combination of biochemical and molecular techniques in cultured cells, xenografts, and engineered mouse models
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refer to http://mbg.au.dk/ for further information about The Department of Molecular Biology and Genetics and to https://nat.au.dk/ and http://www.au.dk/ for information on Faculty of Natural Sciences and
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integrity Validate findings in human tissue via collaboration with the HEETR eye bank (P1-UT), accessing AMD donor eyes for histological and molecular correlation. Model multicellular crosstalk by building
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Sahoo and perform molecular/cellular studies of neuronal development using in vivo (mouse models) and in vitro (cultured primary neurons) models, involving skilled surgical procedures on mice and rats