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Center for Drug Evaluation and Research (CDER) | Silver Spring, Maryland | United States | about 6 hours ago
the regulatory science of targeted therapies, including peptides and oligonucleotide therapeutics (ONTs), through the integration of nonclinical safety data evaluation and Model-Informed Drug Development (MIDD
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experimental and computational models. The doctoral candidate will develop three-dimensional printed models of diseased aortic valves and play a central role in the further development and validation of a
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genomics with advanced computational and AI approaches to develop biologically interpretable clinical models. The study has two complementary aims: Multi-omics discovery in solid tumors - Discover disease
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, and new approaches to treating infectious diseases using complementary in vitro and in vivo infection models. The Gamble Laboratory has expertise in synthetic, bioorganic, and medicinal chemistry, with
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Center for Drug Evaluation and Research (CDER) | Silver Spring, Maryland | United States | about 6 hours ago
will receive training and participate in the design, conduct, optimization, and interpretation of in vitro studies using human-relevant respiratory epithelial models. Experimental activities may include
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developing representations, using neuroimaging with fMRI and OPM-MEG, and to model the developmental process using computational models from AI. The project aims to better understand infant cognition, develop
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Location: The Francis Crick Institute, London Short summary We are seeking an ambitious Postdoctoral Fellow to develop the next generation of deep mechanistic models (DMMs; Fabrini & Fröhlich
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developing representations, using neuroimaging with fMRI and OPM-MEG, and to model the developmental process using computational models from AI. The project aims to better understand infant cognition, develop
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(PDX) models. The position requires proficiency in mouse handling and welfare and in repeated drug administration by oral gavage, intraperitoneal injection, and intravenous tail-vein injection
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vivo models of AD. The candidate will perform the following tasks: 1. Encapsulation of the drug in liposomes and exosomes and their respective characterization; 2. Treatment of neuronal and astrocyte