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Field
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LC-MS/MS method for their analysis in different matrices. The method is further developed by including other fermentation-derived metabolites and is used for analysis of thousands of samples in
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, MALDI mass spectrometry with imaging capabilities, Agilent 6470 triple-quadrupole LC-MS systems, isothermal titration calorimetry, advanced plate readers, and microscopy facilities. Level Scope: After
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, SEM, or Raman. Perform data analysis of mass spectrometry (i.e., GC-MS, LC-MS, SIMS) and microscopy data sets and coordinate between experimental studies and theoretical simulations. Communicate
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into interpretable visualisations for clinical microbiologists and chemists, cross-platform generalisation to high-resolution MALDI (MALDI-2, timsTOF) and LC-MS, and biological extensions such as rare infections
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chromatography. The candidate will prepare samples for immunopeptidomics by liquid chromatography coupled with mass spectrometry tandem (LC-MS/MS), analyze large datasets, and develop scripts and machine learning
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The Pluskal lab at IOCB Prague combines cutting-edge experimental (e.g., LC-MS, metabolomics, RNA-seq) and computational (e.g., bioinformatics, molecular networking, machine learning) approaches
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oversight. Proficient in basic statistical methods and design of MSI / LC-MS experiments and techniques. 3+ years of relevant experience in a research or laboratory environment including: Working knowledge
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Sciences, or a related discipline, with demonstrated hands-on experience in LC-MS-based metabolomics. The candidate will also be encouraged to apply for external postdoctoral funding and contribute to grant
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peer-reviewed publication record is preferred. Proficiency in compound purification and characterization using techniques such as chromatography, HPLC, LC-MS, and NMR. FLSA Exempt Full Time/Part Time
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, immunohistochemistry, flow cytometry, and cytokine profiling. · Coordinate metabolomic studies including sample preparation and collaboration with the metabolomics core for LC-MS/MS analysis of GABA, butyrate, and