Open Rank Laboratory Sciences Professional - Mosimann Lab

Job Summary:

A position as a Laboratory Sciences Professional (open rank) is available within the Mosimann research laboratory in the Department of Pediatrics, Section of Developmental Biology, at the University of Colorado Denver-Anschutz Medical Campus. This is a full-time (1.0FTE) position that will utilize molecular, biochemical, genetic, imaging and bioinformatic/computational approaches in a wet lab setting.

The Mosimann lab studies the formation of the heart, blood, and blood vessels as well as their developmentally related cell types using zebrafish as principal model. As a Laboratory Sciences Professional in our lab, you will work closely with graduate students and postdoctoral fellows to support their projects, as well as pursue individual lines of research. The work is highly flexible and variable and includes standard molecular biology techniques (PCR, subcloning, gel electrophoresis), microscopy (fluorescence and confocal microscopy), transgenesis techniques, and basic computational/bioinformatic analyses. Commensurate with increased expertise, you will be given the opportunity to work more independently on projects using state-of-the-art methods such as scRNAseq and scMultiome analyses, transgenesis, CRISPR-Cas9, and more.

Key Responsibilities:

• Provide general support to laboratory staff and PI.
• Order reagents and materials and oversee inventory.
• Maintain laboratory stocks and buffers.
• Maintain laboratory records, supplies, samples in an organized manner.
• Maintain the laboratory and equipment in working and clean condition.
• Maintain laboratory compliance with environmental health and safety regulations.
• Collect, accurately record, and analyze data in conjunction with research staff.
• Utilize, care for, and maintain zebrafish for research.
• Perform standard molecular/biochemical assays, including PCR, cloning, gel electrophoresis, and western blots.
• Perform in situ RNA hybridization and immunohistochemistry.
• Perform microscopic analyses and basic imaging.
• Use standard bioinformatic/computational tools to analyze data sets
• Additional responsibilities related to the position as assigned by PI

Why Join Us:

The Mosimann research group is part of a highly cohesive, productive academic unit in the Section of Developmental Biology within the Department of Pediatrics. The Section of Developmental Biology is committed to research that improves child health with five main objectives:

• Understand the genetic, molecular, and cellular mechanisms that guide normal development.
• Determine how normal developmental processes are altered to result in developmental disease and disability.
• Identify new diagnostic strategies and molecular and cellular therapies targeted at treatment of childhood disease.
• Train the next generation of leaders in developmental and stem cell biology and pediatric disease research.
• Serve as a hub for basic and translational child health research that spans the Anschutz Medical Campus research community.

To accomplish these objectives the faculty, graduate students, postdoctoral trainees and research staff who comprise the Section of Developmental Biology perform research using stem cell, organoid and animal experimental models, including Drosophila, zebrafish and mice. Our investigations focus on several major tissue and organ systems such as the brain, heart, intestine, face and vascular, olfactory and immune systems. Our work is leading to a better understanding of childhood disabilities associated with neuropsychiatric disease, Down syndrome, the congenital basis of cardiovascular and facial malformations and the impact of maternal health on fetal development.

The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off – vacation, sick, holidays, and more. To see what benefits are available, please visit: https://www.cu.edu/employee-services/benefits-wellness .

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty, and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication, and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community, and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

Intermediate Level:

• Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field.
  • Substitution: A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis.
• Three (3) years professional level research experience.
• One (1) year professional level research experience.

Senior Level:

• Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field.
  • Substitution: A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis.
• Two (2) years professional level research experience.

Principal Level:

• Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
  • Substitution: A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis.
• Three (3) years professional level research experience.

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

• Master’s degree in biology, molecular biology, chemistry, genetics or related field.
• Four (4) or more years of experience in an experimental or wet laboratory.
• Previous experience with bioinformatics/statistics using R, Python or related programming language.
• Previous experience with fluorescence and confocal microscopy.
• Previous lab experience with zebrafish as a model organism.
• Previous experience with the generation of mutant or transgenic animals (using CRISPR/Cas9, homologous recombination, or similar approach).

Knowledge, Skills, and Abilities:

• Proficient knowledge of basic laboratory techniques including safety procedures and techniques.
• Ability to communicate effectively, both in writing and orally.
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
• Outstanding customer service skills.
• Demonstrated commitment and leadership ability to advance diversity and inclusion.
• Ability to interpret and master complex research protocol information.

How to Apply:

For full consideration, please submit the following document(s):

1.     A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2.     Curriculum vitae / Resume

3.     Five professional references including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers .

Questions should be directed to: [email protected]

Screening of Applications Begins:

Applications will be accepted until finalists are identified, but preference will be given to complete applications received by June 15, 2024. Those who do not apply by this date may or may not be considered.

Anticipated Pay Range:

The starting salary range (or hiring range ) for this position has been established as:

•        Intermediate: $48,970 to $62,290
•       Senior: $52,941 to $67,341
•        Principal: $60,882 to $77,442

The above salary range (or hiring range ) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans, and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at [email protected] ​.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students, and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases . If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program .