Bioinformatics Analyst

Updated: about 11 hours ago

Position Description:
The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research's Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.

Job Duties:

  • Provide substantial bioinformatics support for the MoCha clinical laboratory, including the analysis and interpretation of high throughput genomic data
  • Provide expertise in the biological interpretation of results, including mutation impact assessment, expression analysis, statistics support and prioritization of identified loci/genes lists, classification model building and determining correlation with clinical data derived from patients
  • Interact with investigators throughout the entire experimental process from study design to result interpretation including manuscript preparation
  • Provide support to lab staff in the application of basic data analysis and study design
  • Provide bioinformatics knowledge as a shared team resource
  • Maintain and track complex data for multiple projects
  • Work with lab managers to update genetic information in databases
  • Work closely with clinical lab staff to provide computation resources and to support data analysis and storage
  • Coordinate and integrate software applications and databases within the larger group including the Bethesda, Frederick,and Shady Grove NCI campuses

Qualifications:
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
This is a dual level requisition. It may be filled at either a Bioinformatics Analyst II or Bioinformatics Analyst III level.

Basic Qualifications for a Bioinformatics Analyst II:

  • Possession of a Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical science/bioinformatics/math/statistics/computer
  • Foreign degrees must be evaluated for U.S. equivalency
  • A minimum of two (2) years related computational experience in a biological/medical research laboratory environment with a strong background in bioinformatics application development

Basic Qualifications for a Bioinformatics Analyst III:

  • Possession of a Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical science/bioinformatics/math/statistics/computer
  • Foreign degrees must be evaluated for U.S. equivalency
  • A minimum of five (5) years related computational experience in a biological/medical research laboratory environment with a strong background in bioinformatics application development

Both the Bioinformatics Analyst II and III positions require:

  • Experience in next generation sequence analysis (NGS) including quality metrics, mapping, variant calling and biological interpretation, and experience with analysis of large genomic data sets including integration with data available from public or private sources
  • Hands-on experience in data processing and analyzing sequencing, expression and other array data including quality and biological assessment are also essential
  • Proficiency in Unix (Linux) system, scripting and programming languages such as Shell, R, Python, JavaScript, Perl, Java, SQL and bioinformatics tools and database management
  • Statistical analysis of complex biological data
  • Experience and demonstrated success in a team-oriented environment and excellent communication skills (written and oral)
  • Strong organizational skills and information tracking experience for data with complex structure
  • Ability to identify and solve complex problems
  • In‐depth understanding in molecular biology techniques, oncology and clinical research
  • Excellent communication skills (written and oral)
  • Ability to work effectively in a team‐oriented environment
  • Ability to identify and solve complex problems
  • Strong organizational and multitasking skills
  • Must be able to obtain and maintain a Security Clearance

Preferred Quallifications:

  • Peer reviewed publications demonstrating knowledge of the biology of cancer
  • Experience with Ion Torrent systems, including the Ion Reporter system
  • Experience in data integration, database construction, application development and visualization
  • Experience in porting applications to a web environment and working with workflow tools and applications

To Apply:
If interested, please apply on-line for position #637673 at: http://jobs.leidos.com/ShowJob/Id/1221386/Bioinformatics-Analyst-(NCI)/

This position is subject to a background investigation.


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