Postdoctoral Fellow (index no. 2011-00)

31 Jan 2024
Job Information

Organisation/Company

Paul Scherrer Institut Villigen

Research Field

All

Researcher Profile

Recognised Researcher (R2)

Country

Switzerland

Application Deadline

12 Feb 2024 - 12:59 (Europe/Zurich)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

41.5

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Reference Number

2011-00

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences within Switzerland. We perform cutting-edge research in the fields of future technologies, energy and climate, health innovation and fundamentals of nature. By performing fundamental and applied research, we work on sustainable solutions for major challenges facing society, science and economy. PSI is committed to the training of future generations. Therefore, about one quarter of our staff are post-docs, post-graduates or apprentices. Altogether, PSI employs 2200 people.

The Laboratory of Biomedical Research in the BIO Department is looking for a

 

Postdoctoral Fellow
in protein crystallography

Your tasks
We are offering an attractive Postdoc position assessing the potential of Electron diffraction for high-resolution structural analysis of membrane proteins You will work with photosensitive or pharmacologically relevant targets using novel approaches in electron diffraction.

Our group (https://www.psi.ch/en/bio/schertler-group-research ) is focused on studying the mechanism of action of membrane proteins, including structural dynamics and the development of novel optogenetic tools.

The selected candidate will crystallize proteins with already established protocols, optimize the crystal size using focused ion beam scanning electron microscopy (FIBSEM)
milling and collect the data at the transmission electron microscope in diffraction mode. Similar experimental data will be compared to the performance of a table top electron diffractometer prototype which is already used in the pharma field. The project spans from fundamental to applied sciences involving collaborations at the Paul Scherrer Institute and 2 companies, and it gives the candidate the opportunity to gain leading expertise in the X-ray and electron microscopy / diffraction methods.

Requirements

Research Field

All

Education Level

PhD or equivalent

Skills/Qualifications

Your profile

• Available now
• Experience in FIB-SEM manipulation, electron diffraction and/or crystallography would be beneficial

The PSI hosts important facilities required for crystallography: a synchrotron, the X-ray free electron laser SwissFEL and an electron microscopy facility (https://www.psi.ch/en/emf ). The BIO division together with our PSI detector group has developed a unique instrument for electron diffraction with a dedicated ED-detector based on PSI detector technology.

Additional Information
Benefits

We offer
Our institution is based on an interdisciplinary, innovative and dynamic collaboration. You will profit from a systematic training on the job, in addition to personal development possibilities and our pronounced vocational training culture. If you wish to optimally combine work and family life or other personal interests, we are able to support you with our modern employment conditions and the on-site infrastructure.

Additional comments

For further information, please contact Dr Valérie Panneels, email [email protected] .

Please submit your application online by 12 February 2024 (including list of publications and addresses of referees) for the position as a Postdoctoral Fellow (index no. 2011-00).

Paul Scherrer Institut, Human Resources Management, Luca Simen, 5232 Villigen PSI, Switzerland, www.psi.ch

Work Location(s)

Number of offers available

1

Company/Institute

Paul Scherrer Institut

Country

Switzerland

Geofield

Where to apply

Website

https://apply.refline.ch/673278/3311/index.html?lang=en&cid=1

Contact

City

Villigen PSI

Website

http://www.psi.ch/psi-home

STATUS: EXPIRED