Large-scale assessment of molecular docking tools for drug discovery applications (6 months internship)

Updated: over 1 year ago
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Salary and benefits are according to University of Basel standards.

In Prof. Torsten Schwede's group at the Biozentrum of the University of Basel, we develop computational methods for modelling and analysis of protein structures and their molecular properties to better understand biological processes. Within the SIB Swiss Institute of Bioinformatics, we develop SWISS-MODEL (https://swissmodel.expasy.org ), a widely used web-based platform for generating high-accuracy 3D models of protein structures and complexes for application in life sciences.

In our research, we use AI methods to better guide protein modelling, analyse and visualise effects of sequence mutations in protein structure and function, characterise protein-ligand interactions and explore protein variation from an evolutionary perspective with particular interest in the dark proteome and drug discovery automation.



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