High-Content Screening and Automation Expert

The Friedrich Miescher Institute for Biomedical Research (FMI) seeks a highly motivated individual to manage the High Content Screening (HCS) and Automation projects at the Facility for Advanced Imaging and Microscopy. The FMI is a world-class biomedical research institute investigating the molecular mechanisms of health and disease and has state-of-the-art equipment and infrastructure for HCS. The position (100%) will be initially for three years, with the possibility thereafter to become permanent.

Main responsibilities:

• Define best experimental strategies for HCS projects.
• Help with or perform yourself assay development, including cell and organoid culture, staining and clearing.
• Manage compound and CRISPR libraries in coordination with Novartis HCS platforms.
• Help in setting up image acquisition pipelines and troubleshoot the HCS microscopes (Yokogawa CV7000, Molecular Devices IXM confocal).
• Run automated liquid handling robots and setup micro-fluidics devices for HCS but also other application in proteomics and genomics.
• Guide, supervise and train users.
• Perform basic image pre-processing tasks for subsequent image and data analysis steps and interface with in-house image analysis specialists.
• Manage lab resources.

Profile:

• A PhD degree and ideally 3-4 years of experience in HCS and automation
• Experience in fluorescence confocal microscopy (e.g., LSMs, Spinning-Disks)
• Basic knowledge in image and data processing (e.g., ImageJ, CellProfiler, KNIME)
• Basic skills in scripting (e.g., with Metamorph and Python)
• Excellent organizational skills
• The ability to work as a team member
• Strong interest in training PhD students and postdoctoral scientists
• Excellent communication and presentation skills in English 

Please submit your application, including 2-3 names of referees, electronically at www.fmi.ch/opening by September 12, 2021.

For further information please contact Laurent Gelman ([email protected] ).

About the FMI
The Friedrich Miescher Institute for Biomedical Research (FMI), based in Basel, Switzerland, is a world-class biomedical research institute with a two-fold mission: understanding the molecular mechanisms of health and disease, and training international PhD students and postdoctoral fellows. Approximately 340 people, representing 43 nationalities, work at the FMI. The FMI is affiliated with the University of Basel and the Novartis Institutes for BioMedical Research. Learn more: www.fmi.ch