Laboratory Technician: in vivo imaging

The Neuroinflammation group at the LCSB led by Prof. Michael Heneka focuses on the role of immune mechanisms in neurodegenerative diseases, with a particular focus on Alzheimer’s disease.

The research group has an immediate opening for a motivated and talented Laboratory Technician in in vivo imaging (entry- to advanced-level position) with a strong background in working with multi-photon laser scanning microscopy (2 and 3-photon), state-of-the-art imaging analysis and with mouse models of neurodegenerative diseases. In addition to in vivo imaging techniques, tests assessing motor, learning and memory functions will be part of the work. Additional tasks include standard molecular and cellular biology works.

As a general task you will support the group’s daily lab operations, including ordering lab supplies, sample organization and documentation. Experimentally, you will assess the in vivo imaging of intracerebral cell activity using several imaging techniques, including, but not restricted to, 2- and 3-photon laser scanning microscopy and assist with the analysis of the acquired data. Additionally, you will assess animal behavior and in particular learning and memory function using sophisticated new video-based and classical learning and memory paradigms.

Important technical competencies and tasks include, but are not limited to:

• Experience in working with rodent models and FELASA certification
• Solid experience in multi-photon in vivo imaging and with other microscopy techniques
• Knowledge on state-of-the-art analysis methods of acquired imaging information
• Troubleshooting of technical problems related to microscopy and image acquisition
• Knowledge on animal behavior assessment is considered an asset
• Experience with standard techniques of molecular and cellular biology is considered a plus
• Thorough record keeping in a well-organized lab notebook