Postdoctor in

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At the Department of Rheumatology and Inflammation Research, at the Institute of Medicine, the main research areas are inflammation and inflammatory diseases irrespective of whether they are caused by allergies, infections or are autoimmune diseases. The aim is to investigate the underpinning mechanisms behind the inflammation. Several of our researchers also work as senior consultants at the clinics at Sahlgrenska University Hospital, which is a great advantage especially for translational research.

We are seeking an ambitious postdoc with a special interest in immunology which will join Mattias Svensson’s research group (www.svenssonlabgu.com) in order to explore novel roles for innate lymphoid cells (ILC) in inflammation and autoimmunity. The goal of Dr. Svensson’s research group is to provide a detailed characterization of ILC and their interaction with tissue stromal cells in health and disease by utilizing a combination of functional studies in experimental animal models, studies on unique human materials and molecular studies in cell-based assays. We offer a stimulating and enjoyable environment in a translational research team with both clinical and pre-clinical researchers.

Immunology

Rheumatoid Arthritis (RA) is a systemic autoimmune disease that primarily affects joints of the hands, feet and knees. The pathogenesis of RA involves a complex interplay between the immune system and joint stromal cells (e.g. fibroblast-like synoviocytes [FLS]).

Innate lymphoid cells (ILC) are a family of mainly tissue-resident immune cells that are part of our innate immune system. ILC can be found in most tissues of our body, where they help to maintain tissue integrity through interaction with other immune cells and stromal cells.

Although innate lymphoid cells (ILC) have been identified in the joints of patients with RA, their contribution to disease pathogenesis remains largely unknown. Our goal is to determine the function of ILC and their interaction with other cells during RA.

The successful candidate will work on characterizing the role of ILC in development of the autoimmune and inflammatory disease rheumatoid arthritis. Experimental animal models (K/BxN and SKG) as well as unique human materials are used to study the role of ILC in arthritis. In addition, in vitro cell-culture assays are a vital part of this project. Immunological (e.g. flow cytometry), transcriptional (e.g. RNA-seq, ATAC-Seq), histological (e.g. confocal microscopy) and molecular biology (e.g. qPCR, Western Blot) methods will be used for analysis of cells and tissues. The candidate will be encouraged and expected to conduct their research independently and to plan and execute research tasks in a timely manner. Additionally, the candidate is expected to assist in the supervision of students as well as contribute to common lab duties.

To qualify as a postdoctoral researcher the applicant should hold a PhD in a relevant subject. Since postdoctoral constitutes a qualifying appointment for junior researchers, we aim to target those who have a doctoral degree not older than 3 years from the application deadline.

We are looking for an ambitious and motivated candidate with a special interest in immunology. The candidate should have a doctoral degree within immunology and/or rheumatology and at least one publication in relevant field. Previous experience of working with experimental animal models of arthritis, inflammation or autoimmunity is a merit. When assessing the applicant’s qualifications, previous experience of working with immunology (e.g. flow cytometry), molecular and histology methods as well as cell-culture will be taken into account. The candidate should be able to work both independently as well as in a group and have good communications skills (written and spoken) in English. Great emphasis will be placed on the candidate’s personal suitability for the position.

Type of employment: Fixed-term employment, 24 months Extent: 100 % Location: Institute of Medicine, Gothenburg First day of employment: According to agreement   

Mattias Svensson, Researcher, +46 31-786 67 06, [email protected]

Lill Mårtensson-Bopp, Head of Department, +46 31-342 24 92, [email protected]

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- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

 - A CV including a list of publications

- Contact details of two references

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

Please enclose PhD certificate with the application.

Closing date: 2022-03-10

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.