Staff Scientist - Tumor Immunology

Join the forefront of groundbreaking research at the Beckman Research Institute  of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

An exciting opportunity is available in the laboratory of Dr. Heather McGee, MD, PhD, Assistant Professor in the Departments of Radiation Oncology and Immuno-Oncology.

The focus of the lab is to understand how radiation activates tissue resident immune cells in various tumor microenvironments. Their goals are to identify key molecular and immunologic pathways activated by radiation that can be targeted to enhance anti-tumor immunity and/or minimize normal tissue toxicity for gastrointestinal malignancies.

If you have experience with bioinformatics or are interested in learning computational techniques related to tumor immunology, there is an opportunity to work on a project with Dr. Nicholas Banovich from TGen.

As a successful candidate, you will:

• Research spans from in vitro experiments to animal models with transgenic and knock-in reporter mice. You will play a leading role in NIH- and AACR-funded research and will be the first author on presentations and publications.
• You will lead scientific projects at the intersection of immunology and radiobiology.
• Must have a background in tumor immunology, murine tumor models and multicolor flow cytometry, as well as experience managing junior members of the lab.
• You will utilize techniques including murine irradiation, multicolor flow cytometry, multi-plex immunofluorescence, microscopy, Western blots, single cell RNA sequencing and spatial transcriptomics to dissect biologic mechanisms related to radiation that influence the local immune response.
• This position offers the opportunity to be promoted to Assistant Research Professor (non-tenure track) based on performance.