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healthy despite being at high genetic risk of dementia? This project will use cutting-edge genetic and molecular data from large human biobanks to identify molecular factors that help protect against
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appears protective. This inverse relationship provides a powerful genetic entry point to identify pathways that drive vulnerability or resilience genome wide. This project will use computational methods
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POLARIS doctoral network POLARIS is a European Marie Skłodowska-Curie Doctoral Network focused on accelerating therapy development for leukodystrophies: rare genetic disorders affecting the brain's
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20th October 2026 Languages English English English The Department of Biology has a vacancy for a PhD Candidate in Modelling Marine Larval Dispersal and Spatial Population Genetics and Demography
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embeddings, genetic variation (e.g. pQTLs) and experimental perturbation data, rather than relying on curated pathway databases (e.g. KEGG, Reactome) that introduce a human bias. The successful candidate may
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number of genetic mutations in Schizophrenia patients called “rare coding variants.” These mutations change the proteins they produce, but for many of them, we do not yet know the functional consequences
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experimental research in microbiology, molecular biology and microbiome science? Would you like to investigate how human genetic variation influences the oral microbiome and contribute to a better understanding
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, disease monitoring and treatment evaluation. You will work closely with researchers in human genetics, computational biology and clinical neurology and collaborate with POLARIS partners across Europe
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challenge lies in distinguishing genetic from epigenetic effects and establishing a causal relationship between DNA methylation variants and gene expression. In a collaborative project between Utrecht
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mitochondrial biology, a highly specialised clinical service, human genetics, proteomics, bioinformatics and translational science. You will be supervised by Professor Rob Taylor, Dr Sarah Pickett and Professor