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Field
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challenge lies in distinguishing genetic from epigenetic effects and establishing a causal relationship between DNA methylation variants and gene expression. In a collaborative project between Utrecht
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mitochondrial biology, a highly specialised clinical service, human genetics, proteomics, bioinformatics and translational science. You will be supervised by Professor Rob Taylor, Dr Sarah Pickett and Professor
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the molecular mechanisms linking inherited genetic susceptibility to early metabolic dysfunction remain poorly understood. Recent advances in human genetics, single-cell genomics, and functional
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Biology, Molecular Biology, a related field or MD in human Medicine Interest in CRISPR-based genetic screens and gene editing Enthusiasm for working with organoid models (or willingness to learn) Some lab
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The POLARIS training network POLARIS is a European Marie Skłodowska-Curie Doctoral Network focused on accelerating therapy development for leukodystrophies: rare genetic disorders affecting
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, the interplay between genetic variation and human phenotypes, and the development of AI-driven approaches to better understand human biology and disease and to translate these insights into data-driven strategies
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microenvironment structures are associated with genomic features and clinical outcome. Nat Genet 54, 660-669 (2022). Ali, H. R. et al. Imaging mass cytometry and multiplatform genomics define the phenogenomic
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samples, generate and analyse multi-omics data, and help identify biomarkers that can support diagnosis, disease monitoring and treatment evaluation. You will work closely with researchers in human genetics
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. The Postdoctoral Researcher will be responsible for recruiting human subjects, collecting and analyzing human biomechanical, neurophysiological, and clinical data. The role involves collaborating with academic
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, the interplay between genetic variation and human phenotypes, and the development of AI-driven approaches to better understand human biology and disease and to translate these insights into data-driven strategies